Leading vaccine makers are using real-world evidence from across the globe, including from Israel and the United Kingdom, to further assess the safety and effectiveness of their COVID-19 vaccines outside of randomized controlled clinical trials. Among other things, developers are collecting real-world data to gauge how their products protect against asymptomatic transmission, figure out which dosing regimens work best, and better understand whether the vaccines are safe for use in pregnant women. RWE will be “enormously helpful” and informative for...