FDA released Thursday (March 15) its much-anticipated advance notice of proposed rulemaking seeking public input on a standard level of nicotine for combustible cigarettes. In its ANPRM, the agency points to research that suggests levels of .3, .4 or .5 milligrams of nicotine per rod would lead to cigarettes being minimally or non-addictive. FDA's simulations say such a lowering of nicotine levels could avoid 8.5 million deaths by the end of the century. A leading public health advocacy group told...