Experts Recommend FDA Address Obesity Effects On Drugs

Pharmaceutical experts say current regulatory policies don’t address how obesity influences drug behavior in the human body and are urging FDA to implement several regulatory reforms. “A growing body of literature demonstrates that obesity can change the pharmacokinetics of some drugs, including changes in metabolism, clearance, volume of distribution and half-life,” Christina Chow, a pharmacologist at Emerald Lake Safety, and William Dietz, director of STOP Obesity Alliance, wrote in a recent blog in Health Affairs . The authors call for...