Califf Suggests Large Trials Using EHRs, Small Precision Trials To Lower Costs

FDA Commissioner nominee Robert Califf suggests reforming the clinical trials system so that a combination of small, focused trials for precision medicine and very large trials using electronic health records can be conducted at a lower cost and provide information about benefits and risks of therapeutic interventions to specific patients and populations, responding to inquiries from Senate health committee Chair Lamar Alexander (R-TN) and ranking Democrat Patty Murray (WA). Califf, whose nomination will be voted on Tuesday (Jan. 12), also...